ARA-290 Peptide (Cibinetide)

ARA-290 Peptide for Sale — Cibinetide, Research-Grade

Looking to buy ARA-290? Dr Jays Peptides offers the ARA-290 peptide (Cibinetide) for sale as a third-party lab-tested research compound sourced direct from the manufacturer, with documented purity and same-day U.S. shipping. Veteran-owned and trusted by researchers (Trustpilot 4.8).

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ARA-290 is a synthetic 11-amino-acid peptide engineered from the tissue-protective domain of erythropoietin (EPO). Unlike erythropoietin, which stimulates red blood cell production, ARA-290 selectively activates the innate repair receptor (IRR) — triggering tissue-protective and neuroprotective cellular pathways without affecting hematocrit. This makes the ARA-290 peptide a distinctive tool in preclinical research on nerve repair, inflammation, and tissue protection.

ARA-290 Peptide Specifications

ARA-290 Research Areas

Neuropathy and Small Nerve Fiber Research

The most published area of ARA-290 research involves small nerve fiber models. A clinical trial in sarcoidosis patients with small nerve fiber loss examined ARA-290’s effects on corneal nerve fiber density and neuropathic symptom scores, making it one of the few EPO-derived peptides with published human trial data in this area.

Inflammation and Immune Modulation

Through innate repair receptor activation, ARA-290 is studied for its effect on inflammatory cytokine production and macrophage behavior in models of chronic inflammation and autoimmune-adjacent research.

Tissue Protection and Repair

Research models investigate ARA-290 in wound-healing, vascular protection, and metabolic contexts — exploring how tissue-protective signaling can be activated independently of erythropoiesis.

Pros of the ARA-290 Peptide (Research Context)

• Tissue-protective and neuroprotective effects documented in preclinical studies
• Does not increase red blood cell production, unlike erythropoietin
• Well suited to nerve injury, inflammation, and tissue repair models
• Published human trial data exists for small-nerve-fiber research contexts
• Enables receptor-specific (IRR) signaling pathway analysis

Cons of the ARA-290 Peptide (Research Context)

• Limited human clinical data; primarily a laboratory research compound
• Requires proper cold-chain storage and laboratory handling protocols
• Effects in experimental models are still under active investigation
• Strictly for research purposes; not for human use

Selected Research Literature

1. Brines M, et al. ARA 290, a nonerythropoietic peptide engineered from erythropoietin, mediates tissue protection through the innate repair receptor. [PMC]
2. Heij L, et al. Safety and efficacy of ARA 290 in sarcoidosis patients with symptoms of small fiber neuropathy. [PMC]
3. Study of efficacy of ARA 290 on corneal nerve fiber density — registered clinical trial. [ClinicalTrials.gov]

ARA-290 Peptide — Frequently Asked Questions

What is the ARA-290 peptide?

ARA-290 (Cibinetide) is a synthetic 11-amino-acid peptide derived from erythropoietin’s tissue-protective domain. It selectively activates the innate repair receptor and is studied in nerve repair, inflammation, and tissue-protection research.

Is ARA-290 the same as cibinetide?

Yes — cibinetide is the international nonproprietary name for ARA-290. The compound is also referenced as PH-BSP in some research literature.

Does ARA-290 increase red blood cell production?

No. Unlike erythropoietin, ARA-290 is non-erythropoietic — it activates tissue-protective signaling through the innate repair receptor without raising hematocrit, which is precisely why it is studied as a research alternative to EPO.

Is your ARA-290 third-party tested?

Yes. Every batch is third-party lab tested for purity and identity before release, and ships same-day from the US.

How should ARA-290 be stored?

Store the lyophilized vial at -20°C. After reconstitution with bacteriostatic water, refrigerate at 2–8°C and follow standard laboratory protocols.

Related Research Compounds

Researchers studying the ARA-290 peptide often also explore other tissue-repair and signaling research compounds:

• BPC-157 — tissue-integrity and repair signaling research peptide.
• TB-500 — Thymosin Beta-4 fragment for remodeling research.
• LL-37 — antimicrobial peptide for innate-immunity research.
• Thymosin Alpha-1 — immune-modulation research peptide.

Nothing on this page is medical advice.

ARA-290 — Related Compounds & Research Reading

ARA-290 is studied for tissue-protective and anti-inflammatory signaling, so it is often evaluated alongside other repair and inflammation compounds:

• KPV 10mg — α-MSH tripeptide studied for cytokine and NF-κB pathway modulation.
• BPC-157 — gastric pentadecapeptide studied in tissue-repair signaling models.
• TB-500 — Thymosin Beta-4 fragment studied for cellular migration and remodeling.
• LL-37 — cathelicidin peptide studied in innate-immune and inflammation research.
• KLOW blend — four-peptide formulation combining repair and anti-inflammatory components.

For research use only.